Comparison of the protective efficacy between single and combination of recombinant adenoviruses expressing complete and truncated glycoprotein, and nucleoprotein of the pathogenic street rabies virus in mice

Abstract Background Rabies is an important viral zoonosis that causes acute encephalitis and death in mammals. To date, several recombinant vaccines have been developed based on G protein, which is considered to be the main antigen, and these vaccines are used for rabies control in many countries. M...

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Bibliographic Details
Main Authors: Ha-Hyun Kim, Dong-Kun Yang, Jin-Ju Nah, Jae-Young Song, In-Soo Cho
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Virology Journal
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12985-017-0789-2