DDIGIP: predicting drug-drug interactions based on Gaussian interaction profile kernels

Abstract Background A drug-drug interaction (DDI) is defined as a drug effect modified by another drug, which is very common in treating complex diseases such as cancer. Many studies have evidenced that some DDIs could be an increase or a decrease of the drug effect. However, the adverse DDIs maybe...

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Bibliographic Details
Main Authors: Cheng Yan, Guihua Duan, Yi Pan, Fang-Xiang Wu, Jianxin Wang
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Bioinformatics
Subjects:
RLS
Online Access:https://doi.org/10.1186/s12859-019-3093-x