Sinomenine inhibits amyloid beta-induced astrocyte activation and protects neurons against indirect toxicity

Abstract Amyloid beta is a major constituent of the plaques found in the brains of patients suffering from Alzheimer’s disease (AD). A growing body of research work suggests that neuroinflammation plays important roles in the development of AD. Thus, considerable efforts are directed towards identif...

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Bibliographic Details
Main Authors: Deepali Singh, Apurva Agrawal, Chitra Mohinder Singh Singal, Hriday Shanker Pandey, Pankaj Seth, Shiv Kumar Sharma
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Molecular Brain
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13041-020-00569-6