Expression, Purification, and Characterization of a Novel Hybrid Peptide with Potent Antibacterial Activity

Expression, Purification, and Characterization of a Novel Hybrid Peptide with Potent Antibacterial Activity

The hybrid peptide cecropin A (1–8)–LL37 (17–30) (C–L), derived from the sequence of cecropin A (C) and LL-37 (L), showed significantly increased antibacterial activity and minimized hemolytic activity than C and L alone. To obtain high-level production of C&a...

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Bibliographic Details
Main Authors: Xubiao Wei, Rujuan Wu, Lulu Zhang, Baseer Ahmad, Dayong Si, Rijun Zhang
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Molecules
Subjects:
hybrid peptide
fusion expression
Escherichia coli
antibacterial activity
stability
Online Access:http://www.mdpi.com/1420-3049/23/6/1491

Internet

http://www.mdpi.com/1420-3049/23/6/1491

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