Hippocampal-specific insulin resistance elicits behavioral despair and hippocampal dendritic atrophy

Hippocampal-specific insulin resistance elicits behavioral despair and hippocampal dendritic atrophy

Insulin resistance is a major contributor to the neuroplasticity deficits observed in patients with metabolic disorders. However, the relative contribution of peripheral versus central insulin resistance in the development of neuroplasticity deficits remains equivocal. To distinguish between periphe...

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Bibliographic Details
Main Authors: L.P. Reagan, H.B. Cowan, J.L. Woodruff, G.G. Piroli, J.M. Erichsen, A.N. Evans, H.E. Burzynski, N.D. Maxwell, F.Z. Loyo-Rosado, V.A. Macht, C.A. Grillo
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Neurobiology of Stress
Subjects:
Diabetes
Obesity
Depression
Anxiety
Hippocampal plasticity
Insulin receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S235228952100062X

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http://www.sciencedirect.com/science/article/pii/S235228952100062X

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