Rise and dissemination of aminoglycoside resistance: the aac(6')-Ib paradigm

Rise and dissemination of aminoglycoside resistance: the aac(6')-Ib paradigm

Enzymatic modification is a prevalent mechanism by which bacteria defeat the action of antibiotics. Aminoglycosides are often inactivated by aminoglycoside modifying enzymes encoded by genes present in the chromosome, plasmids, and other genetic elements. The AAC(6’)-Ib (aminoglycoside 6’-N-acetyl...

Full description

Bibliographic Details
Main Authors: María Soledad eRamirez, Nikolas eNikolaidis, Marcelo eTolmasky
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Microbiology
Subjects:
inhibition
Transposon
antibiotic resistance
acetyltransferase
integron
mobile elements
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2013.00121/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2013.00121/full

Similar Items