Palmitate and oleate exert differential effects on insulin signalling and glucose uptake in human skeletal muscle cells

Saturated fatty acids are implicated in the development of insulin resistance, whereas unsaturated fatty acids may have a protective effect on metabolism. We tested in primary human myotubes if insulin resistance induced by saturated fatty acid palmitate can be ameliorated by concomitant exposure to...

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Bibliographic Details
Main Authors: Selina Mäkinen, Yen H Nguyen, Paulina Skrobuk, Heikki A Koistinen
Format: Article
Language:English
Published: Bioscientifica 2017-07-01
Series:Endocrine Connections
Subjects:
Online Access:http://www.endocrineconnections.com/content/6/5/331.full