Challenges and Clinical Strategies of CAR T-Cell Therapy for Acute Lymphoblastic Leukemia: Overview and Developments

Challenges and Clinical Strategies of CAR T-Cell Therapy for Acute Lymphoblastic Leukemia: Overview and Developments

Chimeric antigen receptor (CAR) T-cell therapy exhibits desirable and robust efficacy in patients with acute lymphoblastic leukemia (ALL). Stimulated by the revolutionized progress in the use of FDA-approved CD19 CAR T cells, novel agents with CAR designs and targets are being produced in pursuit of...

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Bibliographic Details
Main Authors: Xinjie Xu, Shengkang Huang, Xinyi Xiao, Qihang Sun, Xiaoqian Liang, Sifei Chen, Zijing Zhao, Zhaochang Huo, Sanfang Tu, Yuhua Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
CAR T-cell
application
challenges
access
adverse events
resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.569117/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.569117/full

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