Bi-functional oxidized dextran–based hydrogel inducing microtumors: An in vitro three-dimensional lung tumor model for drug toxicity assays

Cancer is a serious death causing disease having 8.2 million deaths in 2012. In the last decade, only about 10% of chemotherapeutic compounds showed productivity in drug screening. Two-dimensional culture assays are the most common in vitro drug screening models, which do not precisely model the in...

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Bibliographic Details
Main Authors: Dhaval Kedaria, Rajesh Vasita
Format: Article
Language:English
Published: SAGE Publishing 2017-06-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/2041731417718391