Comprehensive profiling of zebrafish hepatic proximal promoter CpG island methylation and its modification during chemical carcinogenesis

<p>Abstract</p> <p>Background</p> <p>DNA methylation is an epigenetic mechanism associated with regulation of gene expression and it is modulated during chemical carcinogenesis. The zebrafish is increasingly employed as a human disease model; however there is a lack of...

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Bibliographic Details
Main Authors: Gong Zhiyuan, Zhan Huiqing, Williams Timothy D, Mirbahai Leda, Chipman J Kevin
Format: Article
Language:English
Published: BMC 2011-01-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/12/3