Endocannabinoid System in Spinocerebellar Ataxia Type-3 and Other Autosomal-Dominant Cerebellar Ataxias: Potential Role in Pathogenesis and Expected Relevance as Neuroprotective Targets

Endocannabinoid System in Spinocerebellar Ataxia Type-3 and Other Autosomal-Dominant Cerebellar Ataxias: Potential Role in Pathogenesis and Expected Relevance as Neuroprotective Targets

Spinocerebellar ataxias (SCAs) are a group of hereditary and progressive neurological disorders characterized by a loss of balance and motor coordination typically associated with cerebellar atrophy. The most prevalent SCA types are all polyQ disorders like Huntington’s disease, sharing the most rel...

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Bibliographic Details
Main Authors: María Gómez-Ruiz, Carmen Rodríguez-Cueto, Eva Luna-Piñel, Mariluz Hernández-Gálvez, Javier Fernández-Ruiz
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Molecular Neuroscience
Subjects:
cannabinoids
endocannabinoid system
autosomal-dominant inherited ataxias
motor incoordination
neuroprotection
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00094/full

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https://www.frontiersin.org/article/10.3389/fnmol.2019.00094/full

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