Opposing actions of sevoflurane on GABAergic and glycinergic synaptic inhibition in the spinal ventral horn.

BACKGROUND: The ventral horn is a major substrate in mediating the immobilizing properties of the volatile anesthetic sevoflurane in the spinal cord. In this neuronal network, action potential firing is controlled by GABA(A) and glycine receptors. Both types of ion channels are sensitive to volatile...

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Bibliographic Details
Main Authors: Veit-Simon Eckle, Sabrina Hauser, Berthold Drexler, Bernd Antkowiak, Christian Grasshoff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3614984?pdf=render