Detection of androgen receptor (AR) and AR-V7 in small cell prostate carcinoma: Diagnostic and therapeutic implications

Objective: Small cell prostate carcinoma (SCPC) is a rare and highly malignant subtype of prostate cancer. SCPC frequently lacks androgen receptor (AR) and prostate-specific antigen (PSA) expression, and often responds poorly to androgen deprivation therapy (ADT). AR splice variant-7 (AR-V7) is a tr...

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Bibliographic Details
Main Authors: Pei Zhao, Yezi Zhu, Liang Cheng, Jun Luo
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Asian Journal of Urology
Online Access:http://www.sciencedirect.com/science/article/pii/S2214388218300754