The clinical significance of serum SCC-Ag combined with CD105 in patients with cervical cancer during the early stage diagnosis

The clinical significance of serum SCC-Ag combined with CD105 in patients with cervical cancer during the early stage diagnosis

Objective: To invest the clinical significance of serum SCC-Ag combined with CD105 in early diagnosis of cervical cancer to provide new ideas for early diagnosis and clinical treatment of cervical cancer. Methods: A total of 74 cases cervical cancer patients were selected as cervical cancer group...

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Bibliographic Details
Main Authors: Ru-Chan Ma, Hong Bi, Sen-Yang Cao
Format: Article
Language:English
Published: Editorial Board of Journal of Hainan Medical University 2016-09-01
Series:Journal of Hainan Medical University
Subjects:
and 52 cases uterine fibroids patients were selected as normal cervical group
serum samples were collected in the early morning fasting condition
SCC-Ag and CD105 were checked by ELISA method
SCC-Ag and CD105 of two groups were analyzed by t-test
and to compare SCC-Ag and CD105 in different TMN staging
lymph gland metastasis and non-lymph gland metastasis in patients with cervical cancer
the correlation analysis was used by Pearson correlation analysis method. Results: These results came from ELISA method
comparing with normal cervical group
the SCC-Ag and CD105 of cervical cancer group increased
the difference was statistically significant. Comparing with Ⅰ period of TMN staging
SCC-Ag and CD105 of Ⅱ period increased
Ⅲ
Ⅳ period increased
the difference was statistically significant. Comparing with Ⅱ period
SCC-Ag and CD105 of Ⅲ
the difference was statistically significant. Comparing with non-lymph gland metastasis
SCC-Ag and CD105 of lymph gland metastasis increased in cervical cancer with surgical treatment
the difference was statistically significant. According to Pearson correlation analysis
SCC-Ag and CD105 were positively correlated. Conclusion: SCC-Ag and CD105 in patients with cervical cancer increase highly
it has important clinical value that of serum SCCAg combined with CD105 in the early diagnosis of cervical cancer
especially it has clinical guiding significance to staging and lymph gland metastasis of cervical cancer
SCC-Ag
CD105
Cervical cancer
Early stage diagnosis
Clinical significance
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