Structural basis of the novel S. pneumoniae virulence factor, GHIP, a glycosyl hydrolase 25 participating in host-cell invasion.

Structural basis of the novel S. pneumoniae virulence factor, GHIP, a glycosyl hydrolase 25 participating in host-cell invasion.

Pathogenic bacteria produce a wide variety of virulence factors that are considered to be potential antibiotic targets. In this study, we report the crystal structure of a novel S. pneumoniae virulence factor, GHIP, which is a streptococcus-specific glycosyl hydrolase. This novel structure exhibits...

Full description

Bibliographic Details
Main Authors: Siqiang Niu, Miao Luo, Jian Tang, Hua Zhou, Yangli Zhang, Xun Min, Xuefei Cai, Wenlu Zhang, Wenchu Xu, Defeng Li, Jingjin Ding, Yonglin Hu, Dacheng Wang, Ailong Huang, Yibin Yin, Deqiang Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3712932?pdf=render

Internet

http://europepmc.org/articles/PMC3712932?pdf=render

Similar Items