mTOR Mysteries: Nuances and Questions About the Mechanistic Target of Rapamycin in Neurodegeneration

The mechanistic target of rapamycin protein complex, mTORC1, has received attention in recent years for its role in aging and neurodegenerative diseases, such as Alzheimer’s disease. Numerous excellent reviews have been written on the pathways and drug targeting of this keystone regulator of metabol...

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Bibliographic Details
Main Authors: Nicholas G. Norwitz, Henry Querfurth
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00775/full