Flavonoid Versus Artemisinin Anti-malarial Activity in Artemisia annua Whole-Leaf Extracts

Flavonoid Versus Artemisinin Anti-malarial Activity in Artemisia annua Whole-Leaf Extracts

Artemisinin, a sesquiterpene lactone produced by Artemisia annua glandular secretory trichomes, is the active ingredient in the most effective treatment for uncomplicated malaria caused by Plasmodium falciparum parasites. Other metabolites in A. annua or related species, particularly flavonoids, hav...

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Bibliographic Details
Main Authors: Tomasz Czechowski, Mauro A. Rinaldi, Mufuliat Toyin Famodimu, Maria Van Veelen, Tony R. Larson, Thilo Winzer, Deborah A. Rathbone, David Harvey, Paul Horrocks, Ian A. Graham
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Plant Science
Subjects:
malaria
Artemisia annua
artemisinin
flavonoids
Plasmodium falciparum
chalcone isomerase
Online Access:https://www.frontiersin.org/article/10.3389/fpls.2019.00984/full

Internet

https://www.frontiersin.org/article/10.3389/fpls.2019.00984/full

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