A novel quantitative hemolytic assay coupled with restriction fragment length polymorphisms analysis enabled early diagnosis of atypical hemolytic uremic syndrome and identified unique predisposing mutations in Japan.

A novel quantitative hemolytic assay coupled with restriction fragment length polymorphisms analysis enabled early diagnosis of atypical hemolytic uremic syndrome and identified unique predisposing mutations in Japan.

For thrombotic microangiopathies (TMAs), the diagnosis of atypical hemolytic uremic syndrome (aHUS) is made by ruling out Shiga toxin-producing Escherichia coli (STEC)-associated HUS and ADAMTS13 activity-deficient thrombotic thrombocytopenic purpura (TTP), often using the exclusion criteria for sec...

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Bibliographic Details
Main Authors: Yoko Yoshida, Toshiyuki Miyata, Masanori Matsumoto, Hiroko Shirotani-Ikejima, Yumiko Uchida, Yoshifumi Ohyama, Tetsuro Kokubo, Yoshihiro Fujimura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4423893?pdf=render

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http://europepmc.org/articles/PMC4423893?pdf=render

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