Involvement of endoplasmic reticulum stress in inflammatory bowel disease: a different implication for colonic and ileal disease?

Involvement of endoplasmic reticulum stress in inflammatory bowel disease: a different implication for colonic and ileal disease?

BACKGROUND: Endoplasmic reticulum (ER) stress has been suggested to play a role in inflammatory bowel disease (IBD). The three branches (ATF6, IRE1 and PERK) of the unfolded protein response (UPR) have different roles and are not necessarily activated simultaneously. METHODOLOGY/PRINCIPAL FINDINGS:...

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Bibliographic Details
Main Authors: Sara Bogaert, Martine De Vos, Kim Olievier, Harald Peeters, Dirk Elewaut, Bart Lambrecht, Philippe Pouliot, Debby Laukens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3196494?pdf=render

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http://europepmc.org/articles/PMC3196494?pdf=render

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