The Role of Vesicle Trafficking Defects in the Pathogenesis of Prion and Prion-Like Disorders
Prion diseases are fatal and transmissible neurodegenerative diseases in which the cellular form of the prion protein ‘PrP<sup>c</sup>’, misfolds into an infectious and aggregation prone isoform termed PrP<sup>Sc</sup>, which is the primary component of prions. Many neurodege...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-09-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/19/7016 |