The Helicobacter pylori HopQ outermembrane protein inhibits immune cell activities

The Helicobacter pylori HopQ outermembrane protein inhibits immune cell activities

We previously showed that the colorectal cancer colonizing bacterium Fusobacterium nucleatum protects tumors from immune cell attack via binding of the fusbacterial Fap2 outer-membrane protein to TIGIT, a checkpoint inhibitory receptor expressed on T cells and NK cells. Helicobacter pylori, the caus...

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Bibliographic Details
Main Authors: Chamutal Gur, Naseem Maalouf, Markus Gerhard, Bernhard B. Singer, Johanna Emgård, Violeta Temper, Tzahi Neuman, Ofer Mandelboim, Gilad Bachrach
Format: Article
Language:English
Published: Taylor & Francis Group 2019-04-01
Series:OncoImmunology
Subjects:
helicobacter pylori
ceacam1
immune cells
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1553487

Internet

http://dx.doi.org/10.1080/2162402X.2018.1553487

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