Acute myocardial infarction occurring while on chronic clopidogrel therapy ('clopidogrel failure') is associated with high incidence of clopidogrel poor responsiveness and stent thrombosis.

The clinical significance of the laboratory-based phenomenon of clopidogrel hypo-responsiveness and platelet reactivity associated with acute myocardial infarction, despite chronic clopidogrel therapy, is largely unknown. We aimed to determine platelet reactivity and clinical and angiographic featur...

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Bibliographic Details
Main Authors: Ehud Regev, Elad Asher, Paul Fefer, Roy Beigel, Israel Mazin, Shlomi Matetzky, Platelets and Thrombosis in Sheba (PLATIS) - Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5889184?pdf=render