Molecular mechanisms of antitumor activity of taxanes. I. Interaction of docetaxel with microtubules
Docetaxel (Taxotere), a new semisynthetic taxoid, is a mitotic inhibitor, widely used in monotherapy or in combination with other anticancer drugs against many types of cancer. The structure and dynamics of microtubules as the main target for docetaxel activity inside the cell and the taxane-binding...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Index Copernicus International S.A.
2010-11-01
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Series: | Postępy Higieny i Medycyny Doświadczalnej |
Subjects: | |
Online Access: | http://journals.indexcopernicus.com/fulltxt.php?ICID=923813 |