Molecular mechanisms of antitumor activity of taxanes. I. Interaction of docetaxel with microtubules

Docetaxel (Taxotere), a new semisynthetic taxoid, is a mitotic inhibitor, widely used in monotherapy or in combination with other anticancer drugs against many types of cancer. The structure and dynamics of microtubules as the main target for docetaxel activity inside the cell and the taxane-binding...

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Bibliographic Details
Main Authors: Sabina Tabaczar, Aneta Koceva-Chyła, Karolina Matczak, Krzysztof Gwoździński
Format: Article
Language:English
Published: Index Copernicus International S.A. 2010-11-01
Series:Postępy Higieny i Medycyny Doświadczalnej
Subjects:
Online Access:http://journals.indexcopernicus.com/fulltxt.php?ICID=923813