Soluble HLA-G and HLA-G Bearing Extracellular Vesicles Affect ILT-2 Positive and ILT-2 Negative CD8 T Cells Complementary

Soluble HLA-G and HLA-G Bearing Extracellular Vesicles Affect ILT-2 Positive and ILT-2 Negative CD8 T Cells Complementary

Tumor immune escape is associated with both, the expression of immune checkpoint molecules on peripheral immune cells and soluble forms of the human leukocyte antigen-G (HLA-G) in the blood, which are consequently discussed as clinical biomarker for disease status and outcome of cancer patients. HLA...

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Bibliographic Details
Main Authors: Esther Schwich, Gia-Gia T. Hò, Joel LeMaoult, Christina Bade-Döding, Edgardo D. Carosella, Peter A. Horn, Vera Rebmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
HLA-G
ILT-2
immune checkpoint
extracellular vesicles
exosomes
breast cancer
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.02046/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.02046/full

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