Absence epilepsy in apathetic, a spontaneous mutant mouse lacking the h channel subunit, HCN2

Analysis of naturally occurring mutations that cause seizures in rodents has advanced understanding of the molecular mechanisms underlying epilepsy. Abnormalities of Ih and h channel expression have been found in many animal models of absence epilepsy. We characterized a novel spontaneous mutant mou...

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Bibliographic Details
Main Authors: Wendy K. Chung, Minyoung Shin, Thomas C. Jaramillo, Rudolph L. Leibel, Charles A. LeDuc, Stuart G. Fischer, Efthia Tzilianos, Ayman A. Gheith, Alan S. Lewis, Dane M. Chetkovich
Format: Article
Language:English
Published: Elsevier 2009-03-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108003082