Small Molecules Enable Cardiac Reprogramming of Mouse Fibroblasts with a Single Factor, Oct4

Small Molecules Enable Cardiac Reprogramming of Mouse Fibroblasts with a Single Factor, Oct4

It was recently shown that mouse fibroblasts could be reprogrammed into cells of a cardiac fate by forced expression of multiple transcription factors and microRNAs. For ultimate application of such a reprogramming strategy for cell-based therapy or in vivo cardiac regeneration, reducing or eliminat...

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Bibliographic Details
Main Authors: Haixia Wang, Nan Cao, C. Ian Spencer, Baoming Nie, Tianhua Ma, Tao Xu, Yu Zhang, Xiaojing Wang, Deepak Srivastava, Sheng Ding
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714000722

Internet

http://www.sciencedirect.com/science/article/pii/S2211124714000722

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