Development of cell mediated immunity to flagellar antigens and acquired resistance to infection by Trypanosoma cruzi in mice

Modulation by BCG and/or cyclophosphamide of sensitization of mice with flagellar fraction (a tubulin-enriched fraction) prevented death of mice challenged with T. cruzi CL strain trypomastigotes recovered from Vero cells. A methodology was ceveloped to assay specific antigens and to determine optim...

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Bibliographic Details
Main Authors: S. C. Gonçalves da Costa, P. H. Lagrande
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 1981-12-01
Series:Memórias do Instituto Oswaldo Cruz.
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761981000400005