Myofilament calcium sensitivity: Role in regulation of in vivo cardiac contraction and relaxation

Myofilament calcium sensitivity is an often-used indicator of cardiac muscle function, often assessed in disease states such as hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM). While calcium sensitivity measurement provides important insights into the mechanical force-generating c...

Full description

Bibliographic Details
Main Authors: Jae-Hoon Chung, Brandon J Biesiadecki, Mark T Ziolo, Jonathan P Davis, Paul M L Janssen
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-12-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00562/full