Cytokeratin 5 determines maturation of the mammary myoepithelium

Summary: At invasion, transformed mammary epithelial cells expand into the stroma through a disrupted myoepithelial (ME) cell layer and basement membrane (BM). The intact ME cell layer has thus been suggested to act as a barrier against invasion. Here, we investigate the mechanisms behind the disrup...

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Bibliographic Details
Main Authors: Vivi Deckwirth, Eeva Kaisa Rajakylä, Sandhanakrishnan Cattavarayane, Anna Acheva, Niccole Schaible, Ramaswamy Krishnan, Juan José Valle-Delgado, Monika Österberg, Pia Björkenheim, Antti Sukura, Sari Tojkander
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221003813