[1–9-NαC]-linusorb B2 and [1–9-NαC]-linusorb B3 isolated from flaxseed induce G1 cell cycle arrest on SGC-7901 cells by modulating the AKT/JNK signaling pathway

Linoorbitides (LOBs) are a family of naturally-occurring cyclic peptides in flaxseed. Previously, we reported that two different structural LOBs, [1–9-NαC]-linusorb B2 and [1–9-NαC]-linusorb B3, induced apoptosis towards SGC-7901 cells through an intrinsic and/or extrinsic pathway. In the present st...

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Bibliographic Details
Main Authors: Xian-Guo Zou, Jiang-Ning Hu, Mei Wang, Ying-Xue Du, Juan Li, Qi-Ying Mai, Ze-Yuan Deng
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S175646461830570X