Probabilistic prioritization of candidate pathway association with pathway score

Probabilistic prioritization of candidate pathway association with pathway score

Abstract Background Current methods for gene-set or pathway analysis are usually designed to test the enrichment of a single gene-set. Once the analysis is carried out for each of the sets under study, a list of significant sets can be obtained. However, if one wishes to further prioritize the impor...

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Bibliographic Details
Main Authors: Shu-Ju Lin, Tzu-Pin Lu, Qi-You Yu, Chuhsing Kate Hsiao
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Bioinformatics
Subjects:
Association study
Bayesian logistic regression
Competing pathways
Differentially expressed genes
Gene-set analysis
Pathway ranking
Online Access:http://link.springer.com/article/10.1186/s12859-018-2411-z

Internet

http://link.springer.com/article/10.1186/s12859-018-2411-z

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