Gasdermin D in peripheral nerves: the pyroptotic microenvironment inhibits nerve regeneration
Abstract Wallerian degeneration (WD) involves the recruitment of macrophages for debris clearance and nerve regeneration, and the cause of the foamy macrophages that are frequently observed in peripheral transection injuries is unknown. Recent studies indicated that these foamy cells are generated b...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-06-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-021-00529-6 |