A novel model of chronic wounds: importance of redox imbalance and biofilm-forming bacteria for establishment of chronicity.

A novel model of chronic wounds: importance of redox imbalance and biofilm-forming bacteria for establishment of chronicity.

Chronic wounds have a large impact on health, affecting ∼6.5 M people and costing ∼$25B/year in the US alone. We previously discovered that a genetically modified mouse model displays impaired healing similar to problematic wounds in humans and that sometimes the wounds become chronic. Here we show...

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Bibliographic Details
Main Authors: Sandeep Dhall, Danh Do, Monika Garcia, Dayanjan Shanaka Wijesinghe, Angela Brandon, Jane Kim, Antonio Sanchez, Julia Lyubovitsky, Sean Gallagher, Eugene A Nothnagel, Charles E Chalfant, Rakesh P Patel, Neal Schiller, Manuela Martins-Green
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4196950?pdf=render

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http://europepmc.org/articles/PMC4196950?pdf=render

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