High-resolution characterization of centriole distal appendage morphology and dynamics by correlative STORM and electron microscopy

The formation of cilia depends on centriole’s distal appendages. Here, the authors use correlative 3D-superresolution, electron microscopy and electron tomography to detail the architecture of distal appendages, to describe the initial stages of appendage assembly and show that appendages of mature...

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Bibliographic Details
Main Authors: Mathew Bowler, Dong Kong, Shufeng Sun, Rashmi Nanjundappa, Lauren Evans, Veronica Farmer, Andrew Holland, Moe R. Mahjoub, Haixin Sui, Jadranka Loncarek
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-08216-4