On the origins of arrestin and rhodopsin

<p>Abstract</p> <p>Background</p> <p>G protein coupled receptors (GPCRs) are the most numerous proteins in mammalian genomes, and the most common targets of clinical drugs. However, their evolution remains enigmatic. GPCRs are intimately associated with trimeric G prote...

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Bibliographic Details
Main Author: Alvarez Carlos E
Format: Article
Language:English
Published: BMC 2008-07-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/8/222