When Cognitive Decline and Depression Coexist in the Elderly: CSF Biomarkers Analysis Can Differentiate Alzheimer's Disease from Late-Life Depression

When Cognitive Decline and Depression Coexist in the Elderly: CSF Biomarkers Analysis Can Differentiate Alzheimer's Disease from Late-Life Depression

Late-life depression (LLD) and Alzheimer's Disease (AD) are the two most frequent neuropsychiatric disorders affecting elderly. LLD and AD may clinically present with depressive and cognitive symptoms. Therefore, when cognitive decline is coupled with depression in the elderly, the differential...

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Bibliographic Details
Main Authors: Claudio Liguori, Mariangela Pierantozzi, Agostino Chiaravalloti, Giulia M. Sancesario, Nicola B. Mercuri, Flaminia Franchini, Orazio Schillaci, Giuseppe Sancesario
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
late-life depression
Alzeimer's disease
CSF biomarkers
beta-amyloid 1-42
tau proteins
18FFDG PET scan
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2018.00038/full

Internet

http://journal.frontiersin.org/article/10.3389/fnagi.2018.00038/full

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