Targeting the Microenvironment in High Grade Serous Ovarian Cancer

Targeting the Microenvironment in High Grade Serous Ovarian Cancer

Cancer–stroma interactions play a key role in cancer progression and response to standard chemotherapy. Here, we provide a summary of the mechanisms by which the major cellular components of the ovarian cancer (OC) tumor microenvironment (TME) including cancer-associated fibroblasts (CAFs)...

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Bibliographic Details
Main Authors: Nkechiyere G. Nwani, Livia E. Sima, Wilberto Nieves-Neira, Daniela Matei
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Cancers
Subjects:
high-grade serous ovarian cancer
tumor microenvironment
angiogenesis
immune response
metastasis
therapeutic targeting strategies
Online Access:http://www.mdpi.com/2072-6694/10/8/266

Internet

http://www.mdpi.com/2072-6694/10/8/266

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