Rift valley Fever virus encephalitis is associated with an ineffective systemic immune response and activated T cell infiltration into the CNS in an immunocompetent mouse model.

Rift valley Fever virus encephalitis is associated with an ineffective systemic immune response and activated T cell infiltration into the CNS in an immunocompetent mouse model.

Rift Valley fever virus (RVFV) causes outbreaks of severe disease in livestock and humans throughout Africa and the Arabian Peninsula. In people, RVFV generally causes a self-limiting febrile illness but in a subset of individuals, it progresses to more serious disease. One manifestation is a delaye...

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Bibliographic Details
Main Authors: Kimberly A Dodd, Anita K McElroy, Tara L Jones, Sherif R Zaki, Stuart T Nichol, Christina F Spiropoulou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4055548?pdf=render

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http://europepmc.org/articles/PMC4055548?pdf=render

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