Two different conformations in hepatitis C virus p7 protein account for proton transport and dye release.

The p7 protein from the hepatitis C virus (HCV) is a 63 amino acid long polypeptide that is essential for replication, and is involved in protein trafficking and proton transport. Therefore, p7 is a possible target for antivirals. The consensus model for the channel formed by p7 protein is a hexamer...

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Bibliographic Details
Main Authors: Siok Wan Gan, Wahyu Surya, Ardcharaporn Vararattanavech, Jaume Torres
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3883635?pdf=render