MECHANISMS OF ATTENUATION OF COLD-ADAPTED STRAIN A/KRASNODAR/101/35/59 (H2N2)

MECHANISMS OF ATTENUATION OF COLD-ADAPTED STRAIN A/KRASNODAR/101/35/59 (H2N2)

Aim. Study of mechanisms of attenuation of cold-adapted (ca) influenza virus strain A/ Krasnodar/101/35/59 (H2N2), associated with disruption of NS1 protein functions. Materials and methods. Study of interferonogenic activity of ca strain A/Krasnodar/101/35/59 (H2N2), its parent variant A/Krasnodar/...

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Bibliographic Details
Main Authors: S. G. Markushin, O. A. Svitich, A. R. Kinkulkina, I. B. Koptyaeva, K. V. Lisovskaya
Format: Article
Language:Russian
Published: Central Research Institute for Epidemiology 2016-04-01
Series: Журнал микробиологии, эпидемиологии и иммунобиологии
Subjects:
attenuation
influenza virus
interferon induction
cpsf-30-ns1 complex
polymerase complex proteins
mutations
Online Access:https://microbiol.elpub.ru/jour/article/view/30

Internet

https://microbiol.elpub.ru/jour/article/view/30

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