Continuous monitoring of neutrophils to lymphocytes ratio for estimating the onset, severity, and subsequent prognosis of immune related adverse events

Continuous monitoring of neutrophils to lymphocytes ratio for estimating the onset, severity, and subsequent prognosis of immune related adverse events

Abstract Immune checkpoint inhibitors (ICIs) play a central role in various cancers. ICIs can cause immune-related adverse events (irAEs). As severe irAEs can be life-threatening, biomarkers for estimating irAE onset are crucial. The neutrophils-to-lymphocytes ratio (NLR) reflects the systemic immun...

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Bibliographic Details
Main Authors: Ryosuke Matsukane, Hiroyuki Watanabe, Haruna Minami, Kojiro Hata, Kimitaka Suetsugu, Toshikazu Tsuji, Satohiro Masuda, Isamu Okamoto, Takashi Nakagawa, Takamichi Ito, Masatoshi Eto, Masaki Mori, Yoichi Nakanishi, Nobuaki Egashira
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79397-6

Internet

https://doi.org/10.1038/s41598-020-79397-6

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