Maternal Antibodies Elicited by Immunization With an O- Polysaccharide Glycoconjugate Vaccine Protect Infant Mice Against Lethal Salmonella Typhimurium Infection

Maternal Antibodies Elicited by Immunization With an O- Polysaccharide Glycoconjugate Vaccine Protect Infant Mice Against Lethal Salmonella Typhimurium Infection

Non-typhoidal Salmonella (NTS) are a leading cause of pediatric invasive bacterial infections in sub-Saharan Africa with high associated case fatality rates in children under 5 years old. We have developed glycoconjugate vaccines consisting of the lipid A-removed surface polysaccharide of NTS, core...

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Bibliographic Details
Main Authors: Scott M. Baliban, Brittany Curtis, Mohammed N. Amin, Myron Mike Levine, Marcela F. Pasetti, Raphael Simon
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
Salmonella
polysaccharide
flagellin
glycoconjugate
vaccine
antibody
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02124/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02124/full

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