MicroRNA-148a regulates low-density lipoprotein metabolism by repressing the (pro)renin receptor.

MicroRNA-148a regulates low-density lipoprotein metabolism by repressing the (pro)renin receptor.

High plasma LDL cholesterol (LDL-c) concentration is a major risk factor for atherosclerosis. Hepatic LDL receptor (LDLR) regulates LDL metabolism, and thereby plasma LDL-c concentration. Recently, we have identified the (pro)renin receptor [(P)RR] as a novel regulator of LDL metabolism, which regul...

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Bibliographic Details
Main Authors: Na Wang, Lishu He, Hui Lin, Lunbo Tan, Yuan Sun, Xiaoying Zhang, A H Jan Danser, Hong S Lu, Yongcheng He, Xifeng Lu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0225356

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https://doi.org/10.1371/journal.pone.0225356

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