Mean field strategies induce unrealistic nonlinearities in calcium puffs

Mean field models are often useful approximations to biological systems, but sometimes, they can yield misleading results. In this work, we compare mean field approaches with stochastic models of intracellular calcium release. In particular, we concentrate on calcium signals generated by the concert...

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Bibliographic Details
Main Authors: Guillermo eSolovey, Daniel eFraiman, Silvina ePonce Dawson
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-08-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2011.00046/full