Antibacterial and EGFR-Tyrosine Kinase Inhibitory Activities of Polyhydroxylated Xanthones from Garcinia succifolia

Antibacterial and EGFR-Tyrosine Kinase Inhibitory Activities of Polyhydroxylated Xanthones from Garcinia succifolia

Chemical investigation of the methanol extract of the wood of Garcinia succifolia Kurz (Clusiaceae) led to the isolation of 1,5-dihydroxyxanthone (1), 1,7-dihydroxyxanthone (2), 1,3,7-trihydroxyxanthone (3), 1,5,6-trihydroxyxanthone (4), 1,6,7-trihydroxyxanthone (5), and 1,3,6,7-tetrahydroxyxanthon...

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Bibliographic Details
Main Authors: Susawat Duangsrisai, Kiattawee Choowongkomon, Lucinda J. Bessa, Paulo M. Costa, Nurmuhammat Amat, Anake Kijjoa
Format: Article
Language:English
Published: MDPI AG 2014-11-01
Series:Molecules
Subjects:
antibacterial activity
antibiotic synergism
EGFR-tyrosine kinase inhibitory activity
Garcinia succifolia
multidrug-resistant bacteria
polyhydroxylated xanthone
Online Access:http://www.mdpi.com/1420-3049/19/12/19923

Internet

http://www.mdpi.com/1420-3049/19/12/19923

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