XIAP regulates cytosol-specific innate immunity to Listeria infection.

The inhibitor of apoptosis protein (IAP) family has been implicated in immune regulation, but the mechanisms by which IAP proteins contribute to immunity are incompletely understood. We show here that X-linked IAP (XIAP) is required for innate immune control of Listeria monocytogenes infection. Mice...

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Bibliographic Details
Main Authors: Laura D Bauler, Colin S Duckett, Mary X D O'Riordan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2516935?pdf=render