Human pluripotent stem-cell-derived alveolar organoids for modeling pulmonary fibrosis and drug testing

Abstract Detailed understanding of the pathogenesis and development of effective therapies for pulmonary fibrosis (PF) have been hampered by lack of in vitro human models that recapitulate disease pathophysiology. In this study, we generated alveolar organoids (AOs) derived from human pluripotent st...

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Bibliographic Details
Main Authors: Jung-Hyun Kim, Geun Ho An, Ji-Young Kim, Roya Rasaei, Woo Jin Kim, Xiong Jin, Dong-Hun Woo, Choongseong Han, Se-Ran Yang, Jong-Hoon Kim, Seok-Ho Hong
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00439-7