Human pluripotent stem-cell-derived alveolar organoids for modeling pulmonary fibrosis and drug testing
Abstract Detailed understanding of the pathogenesis and development of effective therapies for pulmonary fibrosis (PF) have been hampered by lack of in vitro human models that recapitulate disease pathophysiology. In this study, we generated alveolar organoids (AOs) derived from human pluripotent st...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-03-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-021-00439-7 |