A versatile plasmid system for reconstitution and analysis of mammalian ubiquitination cascades in yeast

Ubiquitination is a posttranslational protein modification that regulates most aspects of cellular life. The sheer number of ubiquitination enzymes that are present in a mammalian cell, over 700 in total, has thus far hampered the analysis of distinct protein ubiquitination cascades in a cellular co...

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Bibliographic Details
Main Authors: Rossella Avagliano Trezza, Janny van den Burg, Nico van den Oever, Ben Distel
Format: Article
Language:English
Published: Shared Science Publishers OG 2017-12-01
Series:Microbial Cell
Subjects:
Online Access:http://microbialcell.com/researcharticles/a-versatile-plasmid-system-for-reconstitution-and-analysis-of-mammalian-ubiquitination-cascades-in-yeast/