Septin and Ras regulate cytokinetic abscission in detached cells

Septin and Ras regulate cytokinetic abscission in detached cells

Abstract Background Integrin-mediated adhesion is normally required for cytokinetic abscission, and failure in the process can generate potentially oncogenic tetraploid cells. Here, detachment-induced formation of oncogenic tetraploid cells was analyzed in non-transformed human BJ fibroblasts and BJ...

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Bibliographic Details
Main Authors: Deepesh Kumar Gupta, Siamak A. Kamranvar, Jian Du, Liangwen Liu, Staffan Johansson
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Cell Division
Subjects:
Cytokinesis
Bi-nucleation
Regression
Septin
Ras
Adhesion
Online Access:http://link.springer.com/article/10.1186/s13008-019-0051-y

Internet

http://link.springer.com/article/10.1186/s13008-019-0051-y

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