Serum IL-18 Is Closely Associated with Renal Tubulointerstitial Injury and Predicts Renal Prognosis in IgA Nephropathy

Background. IgA nephropathy (IgAN) was thought to be benign but recently found it slowly progresses and leads to ESRD eventually. The aim of this research is to investigate the value of serum IL-18 level, a sensitive biomarker for proximal tubule injury, for assessing the histopathological severity...

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Bibliographic Details
Main Authors: Beili Shi, Zhaohui Ni, Liou Cao, Minjie Zhou, Shan Mou, Qin Wang, Minfang Zhang, Wei Fang, Yucheng Yan, Jiaqi Qian
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2012/728417